News from International Seminar :Posted: May 2, 2009
Screening Of Benalu Duku For Antiproliferation Of Myeloma Cell
Veterinary Faculty, Airlangga University, Surabaya, Indonesia
Objectives: Loranthaceae dendrophthoe species (Benalu duku) was used commonly in east Java of Indonesia by traditional herbalist to control breast cancer late stadium. The anticancer effect of Loranthaceae dendrophthoe by infuse process of their leaves was evaluated at in vitro experimentally. The objective of this research was to explored anticancer strength of cancer cell by in vitro test.
Methods: Four concentrations of samples (10%, 20%, 30% and 40%) were tested with myeloma cell line in 24 wells microtiterplate. Each concentration were consists of three wells cell lines at more than 1.2.105 cell.ml-1 and examined during the two days post treatment. Similar procedures of Ringer Lactate solution were used as a negative control samples. Implication inhibition activities of Benalu duku were examined by analysis of viabilities cell counted after treated by filtrate samples and comparing with control cells.
Results: The filtrate of Loranthaceae dendrophthoe spec., by infuse process at ranging 20% to 40% was showed inhibition to growing up of myeloma cell (p<0.05).
Conclusions: The studies described above clearly demonstrate that Loranthaceae dendrophthoe species have an ability antiproliferation of cancer culture cell (myeloma cell).
Key words: Anticancer, Antiproliferation, Benalu duku, Myeloma, In vitro test.